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Table 2 Average fold differences in steady-state mRNA levels compared with non-stimulated tenocytes, at 6 h and 24 h of activation, for cell cycle-related genes.

From: Interleukins 4 and 13 modulate gene expression and promote proliferation of primary human tenocytes

mRNA 6 h   24 h  
IL-4 IL-13 IL-4 IL-13
CDK6 2.22 2.26 3.08 2.62
CDKN2B 0.31 0.32 0.22 0.28
CDKN1A 2.21 2.25 -- --
Nibrin 2.97 3.04 -- --
Cyclin B1 -- -- 0.35 0.33
Cyclin B2 -- -- 0.23 0.21
Cyclin E1 -- -- 3.95 3.97
CDK1 -- -- 0.17 0.14
CDK5 -- -- 6.35 2.1
CDKN3 -- -- 0.16 0.19
Cdc20 -- -- 0.24 0.27
Cdc21 -- -- 2.6 2
Cdc46 -- -- 2.78 1.91
GADD45A -- -- 0.37 0.46
HUS1a -- -- 2.72 1.9
Ki-67b -- -- 0.15 0.2
Dp-1c -- -- 2.05 3.64
p53d -- -- 2.63 3.17
  1. For clarity, the standard deviations are not shown, but the variability within each group did not exceed 0.25 cycles of PCR amplification.
  2. -- = difference was > 0.5 but < 2.0; Cdc = cell division cycle; CDK = cyclin-dependent kinase; CDKN = cyclin-dependent kinase inhibitor; GADD45A = growth arrest and DNA-damage-inducible alpha.
  3. aCheckpoint homolog.
  4. bProliferation-related antigen.
  5. cTranscription factor.
  6. dTumor suppressor protein.
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