Figure 1
From: The role of renin angiotensin system inhibition in kidney repair
GFR time-dependent changes over time in the 26 patients on prolonged ramipril therapy in the Ramipril Efficacy in Nephropathy (REIN) study. The breakpoint analysis found that GFR time-dependent changes could not be described by one single first-degree equation, but rather by two different equations describing randomization to 36 months and from 36 to 54 months, respectively. Y1 and Y2 equations describe the interpolating curves before and after the breakpoint, respectively.