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Table 5 mRNA expression of TLRs in patient group and control subjects.

From: Investigation of Toll-like receptors in the pathogenesis of fibrotic and granulomatous disorders: a bronchoalveolar lavage study

  IPF CTD-IP Sarcoidosis Controls P value
TLR-2 9.75 ± 7.54 4.04 ± 3.53 599.9 ± 597.7 1.72 ± 1.63 NS
TLR-3 0.007 ± 0.005 2.03 ± 2 0.038 ± 0.037 0.0014 ± 0.0008 p1:0.001
p4:0.002
p5:0.05
TLR-4 2.34 ± 1.61 1.35 ± 1.12 20.98 ± 19.3 12.37 ± 12.24 NS
TLR-7 5.06 ± 4.12 12.92 ± 10.25 29 ± 26.81 1.5 ± 1.35 p3:0.05
TLR-8 11.14 ± 7.89 14.5 ± 11.65 679.33 ± 672.34 8.67 ± 8.51 NS
TLR-9 3.1 ± 2.51 1.54 ± 0.94 213.52 ± 211.95 0.58 ± 0.53 p6:0.05
  1. Values are expressed as means ± SEM (standard error of the mean). Mann-Whitney U test; P < 0.05 is considered statistically significant. NS, not significant.
  2. p1: P value between IPF and CTD-IPs, p2: P value between IPF and sarcoidosis, p3: P value between IPF and control, p4: P value between CTD-IP and sarcoidosis, p5: P value between CTD-IP and control, p6: P value between sarcoidosis and control.