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Table 4 Expression profile of TLR mRNA in patient group and control subjects.

From: Investigation of Toll-like receptors in the pathogenesis of fibrotic and granulomatous disorders: a bronchoalveolar lavage study

  IPF CTD-IP SARCOIDOSIS CONTROLS P value
TLR-2 100 (16/16) 94.7 (18/19) 100 (14/14) 88.9 (8/9) NS
TLR-3 12.5 (2/16) 78.94 (15/19) 14.3 (2/14) 33.3 (3/9) p1:< 10-4 p4: < 10-4
p5:0.01
TLR-4 93.75 (15/16) 89.4 (17/19) 85.7 (12/14) 77.7 (7/9) NS
TLR-7 93.75 (15/16) 94.7 (18/19) 100 (14/14) 77.7 (7/9) NS
TLR-8 100 (16/16) 100 (19/19) 92.9 (13/14) 100 (9/9) NS
TLR-9 100 (16/16) 100 (19/19) 92.9 (13/14) 77.7 (7/9) p3:0.04
p5:0.03
  1. χ2 test; P < 0.05 is considered statistically significant. NS, not significant. p1: P value between IPF and CTD-IPs, p2: P value between IPF and sarcoidosis, p3: P value between IPF and control, p4: P value between CTD-IP and sarcoidosis, p5: P value between CTD-IP and control, p6: P value between sarcoidosis and control.