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Table 4 Expression profile of TLR mRNA in patient group and control subjects.

From: Investigation of Toll-like receptors in the pathogenesis of fibrotic and granulomatous disorders: a bronchoalveolar lavage study

 

IPF

CTD-IP

SARCOIDOSIS

CONTROLS

P value

TLR-2

100 (16/16)

94.7 (18/19)

100 (14/14)

88.9 (8/9)

NS

TLR-3

12.5 (2/16)

78.94 (15/19)

14.3 (2/14)

33.3 (3/9)

p1:< 10-4 p4: < 10-4

p5:0.01

TLR-4

93.75 (15/16)

89.4 (17/19)

85.7 (12/14)

77.7 (7/9)

NS

TLR-7

93.75 (15/16)

94.7 (18/19)

100 (14/14)

77.7 (7/9)

NS

TLR-8

100 (16/16)

100 (19/19)

92.9 (13/14)

100 (9/9)

NS

TLR-9

100 (16/16)

100 (19/19)

92.9 (13/14)

77.7 (7/9)

p3:0.04

p5:0.03

  1. χ2 test; P < 0.05 is considered statistically significant. NS, not significant. p1: P value between IPF and CTD-IPs, p2: P value between IPF and sarcoidosis, p3: P value between IPF and control, p4: P value between CTD-IP and sarcoidosis, p5: P value between CTD-IP and control, p6: P value between sarcoidosis and control.
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Fibrogenesis & Tissue Repair

ISSN: 1755-1536

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