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Table 2 Demographic and lung function characteristics of patient groups.

From: Investigation of Toll-like receptors in the pathogenesis of fibrotic and granulomatous disorders: a bronchoalveolar lavage study

Characteristics Controls IPF CTD-IP SARC P value
Number 11 16 16 14 -
Age* 58.44 ± 3.49 67.27 ± 1.62 64.23 ± 4.29 47.42 ± 4.65 p2:0.001 p3:0.04 p4:0.01
Gender:
(male/female)**
8/3 12/4 3/13 5/9 p1: < 10-4 p2:0.02
p5:0.002
p6:0.04
Nonsmokers** 3 6 14 5 p1: 0.00 p4:0.004 p5:0.001
Smokers** 7 1 1 4 p3:0.001 p5:0.001
Ex-smokers** 1 9 1 5 p1:0.003 p3:0.02
FEV1* 85.11 ± 7.89 82.44 ± 6.15 86.93 ± 6.37 89.83 ± 6.96 NS
FVC* 91.56 ± 7.46 76.06 ± 5.23 81.07 ± 5.65 91.75 ± 5.97 p2:0.06
FEV1/FVC* 74.56 ± 4.48 85.14 ± 2.76 85.36 ± 2.57 81.36 ± 2.63 p5:0.057
DLCO* 76.22 ± 7.72 54.19 ± 7.18 60.15 ± 5.12 91.3 ± 8.06 p2:0.002 p3:0.05 p4:0.005
KCO* 86.22 ± 8.14 87.63 ± 6.44 79 ± 6.92 108.9 ± 5.91 p2:0.02 p4:0.003 p6:0.04
  1. Values are expressed as means ± SEM (standard error of the mean).
  2. *t-test; P < 0.05 is considered statistically significant.
  3. **χ2 test; P < 0.05 is considered statistically significant.
  4. NS, not significant.
  5. Abbreviations: FEV1: forced expiratory volume in one second, FVC: forced vital capacity, TLC: total lung capacity, DLCO, diffusing capacity for carbon monoxide, KCO: DLCO per unit lung volume. p1: P value between IPF and CTD-IPs, p2: P value between IPF and sarcoidosis, p3: P value between IPF and control, p4: P value between CTD-IP and sarcoidosis, p5: P value between CTD-IP and control, p6: P value between sarcoidosis and control.