Figure 2
From: T regulatory cells and attenuated bleomycin-induced fibrosis in lungs of CCR7-/- mice
Global Increase in inflammatory mediators observed in lungs of untreated CCR7-/- mice. ELISA analysis of (A) interferon (IFN)γ, (B) C10, (C) IFN-inducible protein (IP)-10, (D) monocyte chemotactic protein (MCP)-1, (E) interleukin (IL)-10, (F) tumor necrosis factor-α, (G) IL-12, (H) monocyte chemotactic protein (MIP)1-α, (I) chemokine (C-C motif) ligand (CCL)17, (J) IL-4, (K) CXC chemokine ligand (CXCL)1, (L) transforming growth factor-β and (M) IL-13 in whole lung homogenates from untreated wild type (WT) and C-C chemokine receptor (CCR)7-/- mice and in WT and CCR7-/- mice at day 21 after bleomycin challenge. Data are mean ± SEM from four to five mice at each time point. *P < 0.1).