Figure 1
From: T regulatory cells and attenuated bleomycin-induced fibrosis in lungs of CCR7-/- mice
CCR7-/- mice exhibit decreased collagen deposition in response to bleomycin. (A) Representative histologic sections of mouse lungs. Mouse lung from (a) wild type ( WT) and (b) C-C chemokine receptor (CCR)7-/- mouse 21 days after bleomycin treatment. Masson-trichrome stain. (B) Hydroxyproline levels in whole lung homogenates from untreated or bleomycin-challenged mice. Data are mean ± SEM from four to five mice at each time point, and are representative of three separate experiments. **P < 0.01.