Figure 5From: Mast cells and hypoxia drive tissue metaplasia and heterotopic ossification in idiopathic arthrofibrosis after total knee arthroplastySummary of findings of arthrofibrotic progression. Green arrows indicate normal healing pathway, red arrows highlight disease progression pathway. The orange box indicates the etiology of the oxidative fibrotic transformation process supported by our previous studies [13]. The purple box indicates the pathology of metaplastic heterotopic ossification, supported by this study.Back to article page