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Figure 5 | Fibrogenesis & Tissue Repair

Figure 5

From: Mast cells and hypoxia drive tissue metaplasia and heterotopic ossification in idiopathic arthrofibrosis after total knee arthroplasty

Figure 5

Summary of findings of arthrofibrotic progression. Green arrows indicate normal healing pathway, red arrows highlight disease progression pathway. The orange box indicates the etiology of the oxidative fibrotic transformation process supported by our previous studies [13]. The purple box indicates the pathology of metaplastic heterotopic ossification, supported by this study.

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