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Figure 3 | Fibrogenesis & Tissue Repair

Figure 3

From: Mast cells and hypoxia drive tissue metaplasia and heterotopic ossification in idiopathic arthrofibrosis after total knee arthroplasty

Figure 3

Immunohistochemical stain of arthrofibrotic tissue for lactate dehydrogenase (LDH)5. Representative LDH5 immunohistochemical results are shown for (A) fibrotic regions, (B) fibrocartilage/calcified regions and (C) vascular regions of the tissue. (D) Image analysis of LDH5 for the low and high bone volume (BV) groups. There was no significant difference between the two groups. The high magnification insets emphasize the increased LDH5 expression in fibroblasts and chondrocytes. Scale bar = 250 μm.

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