Figure 1

Microcomputed tomography (microCT) analysis of the periarticular tissue and comparison of bone volume (BV) and range of motion (ROM). Representative microCT images are shown for (A) minimal calcification in pre-surgical osteoarthritic tissues (n = 5), (B) low BV group (0.07 ± 0.02 mm³ of hydroxyapatite; n = 5) and (C) high BV group (7.4 ± 2.7 mm³; n = 5). Calcified regions adjoining the fibrocartilage were confirmed by microCT analysis to have the appearance and density consistent with newly formed bone. (D) ROM and BV comparisons; the closer the patient ROM was to normal flexion, the lower the amount of tissue calcification or BV. Once the ROM was restricted to < 50 degrees, BV increased, and reached a peak when ROM was ≤ 20 degrees.