Figure 3
From: Serum amyloid P ameliorates radiation-induced oral mucositis and fibrosis
Attenuation of radiation-induced mucositis with an altered serum amyloid P (SAP) dosing schedule. Hamsters were exposed to radiation and treated with SAP (2 mg/kg, i.p. every 2 days from day 0 to 12, daily from days 0 to 7, or every 2 days from days -1 to 26 (n = 12 per group) or vehicle control (phosphate-buffered saline (PBS), i.p. every 2 days from days 0 to 12; n = 12). (A) Mean mucositis scores were determined in PBS (vehicle)-treated (open symbols) and SAP-treated (filled symbols) animals from days 6 to 28. (B) The total number of days that hamsters had a mucositis score of ≥ 3 was calculated. *P < 0.05, **P < 0.01 compared with PBS vehicle-treated control irradiated hamster cheek pouches.