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Figure 1 | Fibrogenesis & Tissue Repair

Figure 1

From: The Pin 1 inhibitor juglone attenuates kidney fibrogenesis via Pin 1-independent mechanisms in the unilateral ureteral occlusion model

Figure 1

Juglone reduced fibrogenesis after unilateral ureteral obstruction (UUO). Male Lewis rats (3 months old) underwent UUO of the left kidney for 2 weeks. There were three groups receiving vehicle or juglone (0.25 mg/kg/day or 1 mg/kg/day) for 2 weeks starting the day of surgery. (a) Immunoblot analyses of left kidney from control or juglone-treated rats for the proteins shown along the left. (b) Multiple (n = 3) immunoblots were quantitated and signals expressed as arbitrary units after normalization to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) signal.

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Fibrogenesis & Tissue Repair

ISSN: 1755-1536

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