Figure 4
Immunohistochemical analysis of reactive oxygen species/reactive nitrogen species byproducts in periarticular tissue from patients diagnosed with arthrofibrosis. A-C show representative nitrotyrosine immunohistochemistry on (A) control tissue and (B) low bone volume (BV) and (C) high BV arthrofibrotic tissue. Note the large increase in the presence of nitrotyrosine in the fibrotic regions associated with tissues containing high amounts of bone. Magnification 100× for (A-C), micron bar equals 100 μm.