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Figure 6 | Fibrogenesis & Tissue Repair

Figure 6

From: Evaluation of intracellular signalling pathways in response to insulin-like growth factor I in apoptotic-resistant activated human hepatic stellate cells

Figure 6

Western blot analysis for poly (ADP-ribose) polymerase expression. The analysis was conducted with 20 μg of proteins extracted from hepatic stellate cells treated with insulin-like growth factor I(IGF-I), FasL (20 ng/ml)+CHX (50 μg/ml) or IGF-I+FasL+CHX for 24 hours As shown, FasL+CHX could induce cleavage of poly (ADP-ribose) polymerase (lane 3) and this effect was partially inhibited by IGF-I (lane 4). The barogram summarises the results obtained in two independent experiments: * P < 0.05 when compared with incubation with FasL+CHX without IGF-I.

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