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Figure 5 | Fibrogenesis & Tissue Repair

Figure 5

From: Evaluation of intracellular signalling pathways in response to insulin-like growth factor I in apoptotic-resistant activated human hepatic stellate cells

Figure 5

Effect of insulin-like growth factor I on the phosphorylation of two targets, glycogen synthase kinase 3β (panel A) and FKHR (panel B), downstream of Akt activation. Both GSK3β and FHKR were phosphorylated after 15 minutes of incubation with insulin-like growth factor I (lane 4) and the action was PI-3K dependent (lane 5). Barograms summarise the results obtained in three independent experiments (Panel C). * P < 0.05 or a higher degree of significance when compared with stimulation with growth factors without inhibitor.

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Fibrogenesis & Tissue Repair

ISSN: 1755-1536

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