From: Experimental obstructive cholestasis: the wound-like inflammatory liver response
Phase | Response |
---|---|
I. Immediate or nervous | Ischemia/reperfusion |
 | Edema |
 | Oxidative and nitrosative stress |
II. Intermediate or immune | Activation of resident inflammatory cells |
 | Infiltration by inflammatory cells |
 | Toxin and bacterial translocation |
 | Enzymatic stress |
III. Late or endocrine | Angiogenesis |
 | Cell proliferation |
 | Cell specialization |
 | Energetic stress |