Volume 5 Supplement 1

Proceedings of Fibroproliferative disorders: from biochemical analysis to targeted therapies

Proceedings

Edited by Petro E Petrides and David Brenner

Fibroproliferative disorders: from biochemical analysis to targeted therapies. Go to conference site.

Frauenchiemsee, Germany

25-30 September 2010

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  1. Proceedings

    Developmental responses to lung injury: repair or fibrosis

    Lung development is a complex and finely balanced process. Yet the lung has a relatively limited repertoire of responses to injury, which, depending on severity of the injury and developmental stage and suscep...

    David Warburton

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S2

    Published on: 6 June 2012

  2. Proceedings

    The myofibroblast, multiple origins for major roles in normal and pathological tissue repair

    Myofibroblasts differentiate, invade and repair injured tissues by secreting and organizing the extracellular matrix and by developing contractile forces. When tissues are damaged, tissue homeostasis must be r...

    Ludovic Micallef, Nicolas Vedrenne, Fabrice Billet, Bernard Coulomb, Ian A Darby and Alexis Desmoulière

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S5

    Published on: 6 June 2012

  3. Proceedings

    Fibrocytes in health and disease

    Fibrocytes, a group of bone marrow-derived mesenchymal progenitor cells, were first described in 1994 as fibroblast-like, peripheral blood cells that migrate to regions of tissue injury. These cells are unique...

    Adriana Blakaj and Richard Bucala

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S6

    Published on: 6 June 2012

  4. Proceedings

    Connective tissue growth factor in tumor pathogenesis

    Key roles for connective tissue growth factor (CTGF/CCN2) are demonstrated in the wound repair process where it promotes myofibroblast differentiation and angiogenesis. Similar mechanisms are active in tumor-r...

    Annica Jacobson and Janet L Cunningham

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S8

    Published on: 6 June 2012

  5. Proceedings

    Role of matrix metaloproteases in idiopathic pulmonary fibrosis

    Lung fibrosis is the final common pathway of a large variety of chronic lung disorders, named interstitial lung diseases. The most aggressive form is the idiopathic pulmonary fibrosis [IPF] characterized by al...

    Annie Pardo and Moisés Selman

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S9

    Published on: 6 June 2012

  6. Proceedings

    Proteomics approaches to fibrotic disorders

    This review provides an introduction to mass spectrometry based proteomics and discusses several proteomics approaches that are relevant in understanding the pathophysiology of fibrotic disorders and the appro...

    Marjan Gucek

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S10

    Published on: 6 June 2012

  7. Proceedings

    Therapeutic management of intestinal fibrosis induced by radiation therapy: from molecular profiling to new intervention strategies et vice et versa

    Chronic toxicities of locoregional and systemic oncological treatments commonly develop in long-term cancer survivors. Amongst these toxicities, post-radiotherapeutic complications alter patient's quality of l...

    Saad Hamama, Sylvie Delanian, Virginie Monceau and Marie-Catherine Vozenin

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S13

    Published on: 6 June 2012

  8. Proceedings

    Fibrosis in the kidney: is a problem shared a problem halved?

    Fibrotic disorders are commonplace, take many forms and can be life-threatening. No better example of this exists than the progressive fibrosis that accompanies all chronic renal disease. Renal fibrosis is a d...

    Tim D Hewitson

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S14

    Published on: 6 June 2012

  9. Proceedings

    Progression of renal fibrosis: the underestimated role of endothelial alterations

    The vasculature of the kidney is a heterogeneous structure, whose functional integrity is essential for the regulation of renal function. Owing to the importance of the endothelium in vascular biology, chronic...

    Dominique Guerrot, Jean-Claude Dussaule, Panagiotis Kavvadas, Jean-Jacques Boffa, Christos E Chadjichristos and Christos Chatziantoniou

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S15

    Published on: 6 June 2012

  10. Proceedings

    Origin of myofibroblasts in liver fibrosis

    Most chronic liver diseases of all etiologies result in progressive liver fibrosis. Myofibroblasts produce the extracellular matrix, including type I collagen, which constitutes the fibrous scar in liver fibro...

    David A Brenner, Tatiana Kisseleva, David Scholten, Yong Han Paik, Keiko Iwaisako, Sayaka Inokuchi, Bernd Schnabl, Ekihiro Seki, Samuele De Minicis, Christoph Oesterreicher and Kojiro Taura

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S17

    Published on: 6 June 2012

  11. Proceedings

    Fibrosis in systemic sclerosis: common and unique pathobiology

    Fibrosis in systemic sclerosis (SSc), a complex polygenic disease associated with autoimmunity and proliferative/obliterative vasculopathy, shares pathobiologic features in common with other fibrosing illnesse...

    Swati Bhattacharyya, Jun Wei, Warren G Tourtellotte, Monique Hinchcliff, Cara G Gottardi and John Varga

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S18

    Published on: 6 June 2012

  12. Proceedings

    Molecular targets for therapy in systemic sclerosis

    Despite significant advances have been made in the recent years regarding organ-specific therapies, there is no approved 'disease-modifying' antifibrotic drug for systemic sclerosis (SSc) available to date. Al...

    Naoki Iwamoto and Oliver Distler

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S19

    Published on: 6 June 2012

  13. Proceedings

    Primary myelofibrosis and the "bad seeds in bad soil" concept

    Primary Myelofibrosis (PMF) is a chronic myeloproliferative neoplasm characterized by a clonal myeloproliferation and a myelofibrosis. The concomitant presence of neoangiogenesis and osteosclerosis suggests a ...

    Marie-Caroline Le Bousse-Kerdilès

    Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S20

    Published on: 6 June 2012

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